Phosphopantetheine binding acp domain

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August undefined, 2024

WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins138 – ‘acyl carrier proteins (ACPs) and peptidyl carrier proteins (PCPs), also termed thiolation (T) domains’ – during the biosynthesis of fatty acids (FAs) (use ACPs) ( Scheme 23 ), polyketides (PKs) (use ACPs) ( Scheme … WebNov 20, 2024 · Fatty acid and phospholipid metabolism Other PAO1 genes in this class Pathways Functional Predictions from Interpro Search for additional functional domains at the NCBI CDD database website. Go to this protein's …

Modular type I polyketide synthase acyl carrier protein domains …

Web210-kDa -chain contains a KS domain, a ketoacyl reductase (KR), and a phosphopantetheine transferase domain. In addi-tion, the -chain includes an N-terminal ACP, required for the … WebPhosphopantetheine, also known as 4'-phosphopantetheine, is a prosthetic group of several acyl carrier proteins including the acyl carrier proteins (ACP) of fatty acid synthases, ACPs of polyketide synthases, the peptidyl carrier proteins (PCP), as well as aryl carrier proteins (ArCP) of nonribosomal peptide synthetases (NRPS). [1] small closet organization diy

C7QAF4 - UniProt

WebChr: 1 Mapping Details/Browsers Description Predicted to enable acyl binding activity and acyl carrier activity. Predicted to act upstream of or within fatty acid biosynthetic process. … WebJul 5, 2024 · Sequence domains: Thioester reductase-like domain; ACP-like superfamily; Phosphopantetheine binding ACP domain; AMP-dependent synthetase/ligase domain; … WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins138 – ‘acyl carrier proteins (ACPs) and peptidyl carrier … something to talk about 1995 cast

Structure, function and dynamics in acyl carrier proteins

Modular type I polyketide synthase acyl carrier protein …

http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00823 WebPhosphopantetheine-binding. Status. UniProtKB unreviewed (TrEMBL) ... Family and domain databases. Gene3D. ... IPR036736 ACP-like_sf; IPR020806 PKS_PP-bd; IPR009081 PP … small closet pantry designsWebthe S. cerevisiae FAS (19, 20), the missing ACP domain was subsequently located, docked to the KS domain. We have recently purified the S. cerevisiae fatty acid synthase ... third part binding the CoA or ACP phosphopantetheine group that transfers the acyl and malonyl substrates. In the large fungal fatty acid complex, the KS dimers were ... small closet organizers

"WebMar 2, 2010 · 7 malonyl-CoA + hexanoyl- [acyl-carrier protein] = 7 CoA + norsolorinate anthrone + [acyl-carrier protein] + 7 CO (2) + 2 H (2)O. Biochemical function: not assigned. … " - Phosphopantetheine binding acp domain

Phosphopantetheine binding acp domain

Phosphopantetheine-binding site.: (A) Structural superposition of ...

WebThis multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ( [ACP]) domain. Catalytic activity acetyl-CoA + 2n H+ + n malonyl-CoA + 2n NADPH = a long-chain fatty acid + n CO2 + (n+1) CoA + 2n NADP+ 3 publications WebPhosphopantetheine adenylyltransferase (PPAT, EC. 2.7.7.3) catalyzes an essential step in the reaction that transfers an adenylyl group from adenosine tri phosphate (ATP) to 4' …

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WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins 138 – ‘acyl carrier proteins (ACPs) and peptidyl carrier proteins (PCPs), also termed thiolation (T) domains’ – during the biosynthesis of fatty … Hei Sook Sul, ... Li Chen, in Progress in Nucleic Acid Research and Molecular … WebPhosphopantetheine-binding site.: (A) Structural superposition of ATP-bound MsFadD32 and adenylate analog- and phosphopantetheine-bound PA1221 protein. The N- and C …

WebView Lecture_set+5+lipid+synthesis+notes.pdf from CHEM 153C at UCLA Community School-Los Angeles. The input to fatty acid synthesis is acetyl-CoA, which is carboxylated to malonyl-CoA. The WebJun 2, 2011 · Introduction. One of the most distinctive features of fatty acid, nonribosomal peptide and polyketide biosynthetic pathways is the utilization of the acyl carrier protein (ACP) or peptidyl carrier protein (PCP) for the shuttling of biosynthetic intermediates among various catalytic domains or proteins –.The small and highly dynamic ACPs or PCPs can …

WebFeb 20, 2024 · Acyl carrier protein (ACP) domains act as interaction hubs within modular polyketide synthase (PKS) systems, employing specific protein-protein interactions to present acyl substrates to a... WebFeb 17, 2016 · This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain. automatic annotation. Catalytic activity (2E) ... …

WebFeb 20, 2024 · Acyl carrier protein (ACP) domains act as interaction hubs within modular polyketide synthase (PKS) systems, employing specific protein-protein interactions to …

WebJul 22, 2015 · Acyl carrier protein (ACP) Phosphopantetheine binding ACP domain; Structure analysis Details. Assembly composition: monomeric . Entry contents: 1 distinct polypeptide molecule ... Sequence domains: Phosphopantetheine attachment site. Ligands and Environments No bound ligands. No modified residues. small closet shoe organizationWebNov 13, 2013 · 4ihh: Chasing acyl carrier protein through a catalytic cycle of lipid A production. small closet shelving unitWebJul 10, 2024 · Acyl carrier proteins (ACPs) involved in fatty acid and polyketide synthesis, our main interest here, carry an acyl group attached to the ppt arm via a thioester linkage. … small closets with shelvesWebApr 10, 2024 · HIGHLIGHTS. who: Filamentous Fungi and collaborators from the National Cheng Kung University, Taiwan have published the research work: Transcriptional Activation of Biosynthetic Gene Clusters in Filamentous Fungi, in the Journal: (JOURNAL) how: This Tet-On system was applied with A. fumigatus for inducible expression of the gene of … small closet organizer systemWebPhosphopantetheine (or pantetheine 4' phosphate) is the prosthetic group of acyl carrier proteins ... small closet hangersWebNov 20, 2024 · Phosphopantetheine binding ACP domain; Chloramphenicol acetyltransferase-like domain superfamily; 3 more domains. Structure analysis Details. Assembly composition: monomeric . Entry contents: 1 distinct polypeptide molecule. Macromolecule: Linear gramicidin synthase subunit A Chains: A, B. Molecule details › ... small closet organizer home depotWebApr 20, 2024 · ACP-like superfamily, phosphopantetheine binding ACP domain, trimeric LpxA–like superfamily, AMP-dependent synthetase–like superfamily, polyketide synthase, phosphopantetheine-binding domain, AMP-dependent synthetase/ligase: −1.20: −2.32: −1.12: 0.117796: 0.537084: g11299: small closet solutions diy