Fstl1 macrophage
WebExpression of inflammatory mediators, including TNF-, IL-6, and MCP-1, was significantly increased in 3T3-L1 adipocytes and RAW264.7 macrophages stimulated with recombinant FSTL1. Macrophages, a major player in obesity-induced inflammation, are recruited into adipose tissue during obesity and activated by multiple factors, including those from ... WebMay 12, 2024 · These results showed that circ-WDR27 repressed M.tb vitality and stimulated pro-inflammatory cytokines in M.tb-infected macrophages by affecting the miR-370-3p/FSTL1 axis. Tuberculosis (TB) is a common disease caused by Mycobacterium tuberculosis (M.tb) infection. Our study was to explore the function and mechanism of …
Fstl1 macrophage
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WebJun 2, 2024 · Objective Asthma, a well-known disease with high morbidity, is characterized by chronic airway inflammation. However, the allergic inflammation mechanisms of follistatin-like protein 1 (FSTL1) have not been elucidated. This study aims to investigate the effects of FSTL1 in ovalbumin (OVA)-induced mice and macrophages on nucleotide … WebFeb 9, 2024 · Objective Follistatin-like protein 1 (FSTL1) is widely recognised as a secreted glycoprotein, but its role in modulating macrophage-related inflammation during liver fibrosis has not been documented.
WebCardiovascular diseases [ edit] FSTL1 protein seems to have a cardioprotective role. FSTL1 attenuated hypertrophy following pressure overload [17] and prevented myocardial ischemia/reperfusion injury in a mouse or pig model of ischemia/reperfusion. [18] Muscle-derived Fstl1 modulates vascular remodelling in response to injury. WebOf particular note was that several gene regulation and macrophage antiinflammatory genes were differentially expressed in an FSTL-1–dependent manner, including the nuclear orphan receptor Nr4a1, also known as Nur77. ... It would have been worth examining FSTL1 SNPs in other cohorts and populations, as well as measuring FSTL-1 levels ...
WebWhile cells of mesenchymal lineage are capable of FSTL1 production, FSTL1 expression is notably absent from cells of hematopoietic lineage under normal physiological conditions. Macrophages and monocytes are, however, capable of taking up FSTL1 at sites of inflammation where FSTL1 stimulation can cause the expression of caspase-1 and its ... WebMar 15, 2024 · FSTL1 silencing largely overturned miR-579-3p knockdown-induced effects in M.tb-infected THP-1 macrophages. Circ_0001490 acted as miR-579-3p sponge to up-regulate FSTL1 in THP-1 macrophages. In conclusion, our results demonstrated that circ_0001490 suppressed M.tb survival and promoted the viability and inflammatory …
WebMay 1, 2014 · Myeloid-specific FSTL1-knockout (FSTL1 M-KO ) mice were constructed to explore the function and mechanism of macrophage FSTL1 in 3 murine models of liver fibrosis induced by carbon tetrachloride ...
WebFollistatin (FS)-like 1 (FSTL1) is a member of the FS-SPARC (secreted protein, acidic and rich in cysteine) family of secreted and extracellular matrix proteins. The functions of FSTL1 have been studied in heart and … how to write an loi for real estatehttp://www.abways.cn/shownews.asp?/1_2 or in nandWebFollistatin-like 1 (FSTL1) functions as a pivotal modulator of inflammation and is implicated in many inflammatory diseases such as rheumatoid arthritis. Here, we report that FSTL1 is strongly upregulated and secreted during osteoclast differentiation of bone marrow-derived macrophages (BMMs) and th … or in music termWebDec 1, 2024 · FSTL1 is reported to induce the release of macrophages- and fibroblasts-derived inflammatory cytokines [14], demonstrating that FSTL1 plays a pro-inflammatory role. Zhang et al. found that miR-32-5p facilitates the survival of M.tb pathogen and restrains the release of inflammatory factors in macrophages, and FSTL1 overexpression … how to write an llcWeb上海博华生物是一家专业的生物试剂供应商，为您提供人凝血因子Ⅲ(FⅢ)Elisa试剂盒Human coagulation ... how to write an mfr usafWebMar 29, 2024 · Follistatin-like 1 (FSTL1) is a secreted glycoprotein displaying expression changes during development and disease, among which cardiovascular disease, cancer, … or in nbrWebCD51 + CD61 (Integrin alpha V + Integrin beta 3) CD51 / Integrin alpha V. CD52 or in ms sql